2010年8月16日星期一

Blood disease lymphoma

The diagnosis of lymphoma relies on clinical manifestations, pathological examination and the necessary supporting inspection. Pathological diagnosis should include the type and extent of disease (staging). Deep lesions on only superficial lymph nodes were without diagnosis is often difficult, need the help of laboratory examinations, described as follows:

Laboratory

First, the blood as early general no special. Anemia seen in late or in combination hemolytic anemia. In addition to white blood cells than normal bone marrow involvement, increased eosinophils, common to HD. About 1/3HD absolute reduction in lymphocytes. Plasma cells and Reed-sternberg cells even found in the peripheral blood. Bone marrow involvement thrombocytopenia, or hypersplenism secondary to splenic function.

Second, bone marrow before bone marrow were not lymphoma, generally without exception. Bone marrow smears in HD to find support Reed-sternberg cells diagnose valuable. This cell size large, a diameter of 15 ~ 20μ, nucleus large, can lobulated, dual-core (Mirror cell) or multi-core. Uneven distribution of chromatin, dense integrated block. Thick, deeply stained nuclear membrane. Nucleolus large garden, up to 8μ, free halo zone around the nucleolus.

Third, biochemical examination of rapid ESR prompted active disease; lactate dehydrogenase increased tumor cell proliferation reflects the speed,> 500 units / L suggest poor prognosis NHL. Progression of serum copper and ferritin increased, decreased remission; zinc opposite. Elevated alkaline phosphatase may be liver or bone involvement. They also may be associated with liver involvement of 5 - nucleotide enzymes. Hypercalcemia prompted a bone violations, such changes can occur before X-ray changes. Increased cerebrospinal fluid β2-microglobulin have prompted the central nervous system involvement.

Fourth, immune abnormalities in patients with HD and other stimuli on the original tuberculin reactivity decreased in vitro lymphocyte transformation rate reduction, the degree of progression of the disease. Normal humoral immunity, immune globulin is usually normal or elevated, to reduce late. NHL, humoral immune abnormalities in some patients, manifested as autoimmune hemolytic anemia, immune thrombocytopenia. Coombs test was positive, a small number of patients have monoclonal hypergammaglobulinemia. Treatment of patients achieved remission, return to normal immune function.

V. biopsy to diagnose the inspection methods are essential. General should be chosen under the neck or axillary lymph nodes, submandibular and groin lymph node due to chronic inflammation often affecting the diagnostic accuracy. Scalene fat pad biopsy of mediastinal or lung lesions have a certain diagnosis.

6, mediastinoscopy mediastinoscopy can be made by biopsy of mediastinal extrapleural access, more convenient security.

7, lower extremity lymphangiography in retroperitoneal lymphoma diagnosis, staging, to judge the efficacy and accuracy of observation of recurrence is a high security simple and examination technique with few complications, and in some ways superior to CT and Sound like a plan, it found that normal-sized lymph node lesions of the internal structural changes.

8, CT, MRI examination can sound like the map found within the chest, retroperitoneal, mesenteric lymph node lesions and the liver and spleen lesions.

9, abdominal examination can clearly spleen, liver and abdominal lymph node involvement, radiation therapy is used to determine the radiation field is essential (pathologic stage). If the same time for splenectomy, but also can avoid the spleen in radiation injury to nearby tissues and organs.

Malignant lymphoma, large cell type, the magnification

About half of the adult non-Hodgkin's lymphoma is the occurrence of large cell lymphoma. As seen in this magnification. They may be related to immunosuppression (eg AIDS), may be T cells or B cell origin. Cell volume, and have a distinct nucleus and abundant cytoplasm. The disease tends to be localized, (lower phase), but the rapid expansion of low-level lymphoma than extranodal greater tendency.

Got lymphoma how to do?

Better prognosis than leukemia, lymphoma, because a majority of patients can be cured. At present, the treatment of lymphoma following methods: (1) chemical treatment; (2) radiation therapy; (3) bone marrow transplantation; (4) immune therapy.

Lymphoma diagnosed mainly by pathology, so once suspected of suffering from lymphoma, lymph node biopsy should be done as soon as possible. After a search lymphoma biopsy experienced consultation, in order to clear subtype, because the subtype and prognosis.

Conditions can be diagnosed after the line PET-CT examination to clear stage of the disease.

Classification according to stage of disease and disease treatment programs can be developed.

If the bone marrow are violated, must be received allogeneic bone marrow transplantation, autologous transplantation because of recurrence is very easy.

Breast lipoma

Lipoma is the most common benign tumor of the body surface, can occur in the fatty tissue of any structure, but the most common body surface, and breast. Mostly occurred in the more obese female patients, age 30 to 50 years old prevalent.

Mainly as a single, round or lobulated soft mass, boundary definition, slow growth, rare malignant.
Treatment of surgical excision.

However, surgery should be thoroughly, if left, will inevitably lead to relapse. Removal of tissue should be sent to pathology, so that combined with other tumors and missed.

Lipoma of Chinese Herbs

Chinese medicine prescriptions

Feng Xie】 【differentiation into the Cou, producing phlegm into the tumor.

Therapeutic】 【phlegm expelling wind, sparse Tongluosanjie.

【Name】 daughter Lioujia party pills.

Composition】 【centipede 18 grams, 18 grams whole insect, Bombyx 18 grams, Chan Yi 18 grams, 18 grams Roasted pangolin, night out 18 grams of sand.

【Usage】 A total of research go-between, the water pan for the pill, such as mung bean big. 3 times a day, 3 grams each time.

【Source】 Wen-Fang

When can breast cancer growth

Young breast cancer patients long after pregnancy is disturbed patients and the clinical doctors, patient age, adjuvant therapy and disease prognosis, and many other factors all affect the choice of patients and doctors. Young breast cancer patients should also be concerned about the time of pregnancy. Mueller and other found 10 months after diagnosis on the prognosis of fertility has protective effects, and 2 to 5 years after birth with non-pregnant patients with risk of death compared with patients gradually decreased, but after 6 months of pregnancy the risk of death in patients may increase, but did not reach statistical significant difference. As more and more relevant results and conclusions of the Yi Zhixing reports, the current basic recognition of 24 months after relapse Ruxian Ai Huanzhe not occurred at least not Zengjia breast cancer pregnancy risk of death after Renshenbingbu increased incidence of teratogenic. Shanghai Ruijin Hospital Breast Center Hanbo 3

According to the current review of existing studies, patients after surgery in June has to pregnancy, the prognosis had no significant adverse effects; take into account patients with breast cancer after 2 to 3 years of relapse peak, the most common time for the surgery recommended by the pregnancy After 2 years later, the axillary lymph node metastasis in patients, it was proposed to consider after 5 years. .

Good prognosis, close follow-up of breast cancer patients and good communication between the premise, the clinician can present the clinical findings on the patient's fertility requirements guidance.

2010年8月14日星期六

Malignant melanoma

Malignant melanoma, also known as malignant melanomas originate in the epidermal melanocytes or nevus cancer. The disease can be seen at any age, more seen in middle-aged and older, women slightly outnumber men. Malignant melanoma is a rare malignant tumor, the incidence of the world prepared to have less than 1 year to 2 / 10 million population, but the annual incidence rate in Australia Kunshilanbang 16/10 million people. Very few black and Asian people contracting this disease. I plan to statistics for the Shanghai region 0.41/10 million people. Over the past that the disease is highly malignant tumor metastasis fast in recent years found that the degree of malignancy is not as high as previously believed, freckle-like moles melanoma, 5-year survival as high as 80% to 90%. Nodular melanoma in the transfer of patients received treatment before the 5-year survival rate of about 50% to 60%.

Traditional medicine knowledge of malignant melanoma of medical books dating back to 2000 years ago, "Canon of Medicine", particularly the late physician Jin Liu Juan child book "Ghost Juan-Zi Liu left side" and the Yuan-Fang Sui physician nest book The "all waiting on the source of the disease," a detailed account of both the "off gangrene" "sunspots" of the clinical manifestations, and malignant melanoma similar. Ming written by physicians "surgical authentic" documents the inside and outside of the disease combined treatment. Traditional medicine on the treatment of malignant melanoma has accumulated rich experience, and the effect of stable, less adverse reactions; to relieve suffering and prolong survival time and improve the quality of life have a greater advantage.

Malignant melanoma of different titles in traditional Chinese medicine. In traditional Chinese medicine, attributed to medicine called "sunspots", "black boil" "off gangrene," "Calendar gangrene" and other areas.

Symptoms of multiple myeloma

Multiple myeloma is a malignant proliferation of plasma cells within bone marrow caused by the bone marrow of multiple malignant tumors. Its incidence in Western countries 2 to 4 / 100 000. Zai Ye Bu Chinese cancer patients with multiple myeloma rare, its incidence in recent years, a growing tendency for Shu, such things to happen and Zhenduan levels and the of the disease deeper understanding related, but may also exist some other factors.

Traditional medicine in the medical texts 2,000 years ago, "Yellow Emperor" in a similar disease has been documented, probably because the disease is relatively rare diseases, medical books in the future is less documented. Traditional medicine on the treatment of multiple myeloma, in addition to drug therapy, there are acupuncture, qigong, herbs and other therapies, and the method is simple, wide applicability, side effects, patients accept and so on.

Multiple myeloma different titles in traditional Chinese medicine. In traditional Chinese medicine, Chinese medicine is similar to "Gubi", "bone loss" and so on.